Woher kommt HCM?

Woher kommt HCM?

Die hypertrophe Kardiomyopathie (HCM) ist eine spezielle Herzmuskelerkrankung. Ihr Hauptmerkmal ist eine verdickte Wand der linken Herzkammer. Die Ursachen sind meist genetisch. Die HCM kann mit den Symptomen einer Herzschwäche und Herzrhythmusstörungen einhergehen und ist nicht heilbar.

Ist HCM vererbbar?

Die hypertrophe Kardiomyopathie (HCM) ist mit einer Häufigkeit von 1:500 (d.h. jeder 500. Einwohner ist von der Erkrankung betroffen) die häufigste genetisch bedingte Herzerkrankung. Sie ist darüber hinaus eine der häufigsten vererbbaren Erkrankungen überhaupt.

How old do Maine Coon cats have to be to get HCM?

Maine Coon cat hypertrophic cardiomyopathy (HCM) usually does not show up until they are an adult although the genetic mutation is present at birth. Most Maine Coons develop the disease after 3 years of age but some do not develop it until much later (6- 8 years of age).

Are Maine Coon cats at risk for hypertrophic cardiomyopathy?

Cats affected by hypertrophic cardiomyopathy are at risk of sudden cardiac death. In Maine Coons, a breed-specific mutation has been found to be associated with increased risk for HCM. Phenotype: Cats affected by hypertrophic cardiomyopathy (HCM) are at risk of sudden cardiac death.

What kind of heart disease does a Maine Coon have?

Hypertrophic cardiomyopathy (HCM) is the commonest form of heart disease in cats and it is very common in Maine coons. With HCM the thickness of the heart wall increases abnormally (Liu et al 1981). This thickening causes multiple problems and at some stage prevents normal heart function and heart failure develops.

Can a Maine Coon have HCM without A31p mutation?

These studies have also identified HCM in cats that do not carry the MYBPC3-A31P. The incidence of HCM in these studies was 5.4\% in cats that were negative for the A31P mutation, and 5.4\% with the mutation. Therefore, the MYBPC3-A31P mutation is not the sole cause of HCM in Maine Coons. The other causes are not known at this time.